Anti-ASPSCR1 Antibody, EPR8615

Also for ASPSCR1 (NM_001251888)

Gene Name	Homo sapiens alveolar soft part sarcoma chromosome region, candidate 1 (ASPSCR1), transcript variant 2
Synonyms:	ASPCR1; ASPL; ASPS; RCC17; TUG; UBXD9; UBXN9
Immunogen	A synthetic peptide corresponding to residues in human Tug was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR8615	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:10,000 - 50,000; IP: 1:10 - 100;
Background	Tug contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). It is a tether, which sequesters GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation with transcription factor TFE3 results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas (1).
Related Pathway

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WB Image

Western blot analysis on (A) K562, (B) 293T, and (C) SW480 cell lysates using anti-Tug RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Tug RabMAb.

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Anti-ASPSCR1 Antibody EPR8615

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