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Anti-GAB1 PHOSPHO Antibody

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SKU Description Amount Price Availability*  
TA310016
  • Rabbit anti-GAB1 (Phospho-Tyr627) polyclonal antibody(Phospho-specific)
100ug $325 In Stock

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WB(1)

OriGene Data

ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from humanGab1 around the phosphorylation site of tyrosine 627 (V-E-YP-L-D).
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500~1:1000
Bufferphosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reference Data

Target NameHomo sapiens GRB2-associated binding protein 1 (GAB1), transcript variant 2
Alternative NameGRB2-associated binding protein 1
Database LinkNP_002030
Entrez Gene 2549 Human
Entrez Gene 14388 Mouse
Function
Related PathwayDruggable Genome ErbB signaling pathwayNeurotrophin signaling pathwayRenal cell carcinoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of extracts from HUVEC cells untreated or treated with EGF (200ng/ml, 15min), using Gab1 antibody (Lanes 1 and 2) and Gab1 (phospho-Tyr627) antibody (Lanes 3 and 4).
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