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Anti-BEST1 Antibody E6-6
Also for BEST1 (NM_004183)
|Synthetic peptide conjugated to KLH [KDHMDPYWALENRDEAHS]. |
|Human, Porcine, Primate
||Lot dependent; please refer to CoA along with shipment
|0.1% Sodium Azide|
|Homo sapiens bestrophin 1 (BEST1), transcript variant 1|
|ARB; BEST; BMD; RP50; TU15B; VMD2|
Entrez Gene 7439 Human
|Best macular dystrophy (BMD) or vitelliform macular dystrophy (VMD2), is an autosomal form of macular degeneration, characterized by a depressed light peak in the electrooculogram (EOG). It is inherited and has an early onset. Bestrophin is a 68 kDa basolateral plasma membrane protein encoded by the VMD2 gene. Bestrophin's function is still unknown, but data suggests that it is a chloride channel that plays a role in generating the altered EOG in Best disease patients. In addition, Bestrophin is a useful biochemical and histological marker of RPE (retinal pigment epithelial cells) cells.|
|Ion Channels: OtherTransmembraneDruggable Genome |
* Availability is in business days
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Western Blot: Bestrophin Antibody (E6-6) - Western blot detection of Bestrophin (68 kDa) from human RPE cell lysate.