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Home Antibody All anti-BEST1 antibodies

Anti-BEST1 Antibody E6-6

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA309586 Mouse Monoclonal Bestrophin 1 Antibody (E6-6) 0.1ml $325 3-7 Days
LC418161 BEST1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
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Also for BEST1 (NM_004183)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenSynthetic peptide conjugated to KLH [KDHMDPYWALENRDEAHS].
Clone NameE6-6 IsotypeIgG1 Kappa
Species ReactivityHuman, Porcine, Primate ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB, IF
Predicted MW Explanation 68 kDa
Buffer0.1% Sodium Azide
Purification Ascites

Reference Data

Target NameHomo sapiens bestrophin 1 (BEST1), transcript variant 1
Alternative NameARB; BEST; BMD; RP50; TU15B; VMD2
Database LinkNP_004174
Entrez Gene 7439 Human
FunctionBest macular dystrophy (BMD) or vitelliform macular dystrophy (VMD2), is an autosomal form of macular degeneration, characterized by a depressed light peak in the electrooculogram (EOG). It is inherited and has an early onset. Bestrophin is a 68 kDa basolateral plasma membrane protein encoded by the VMD2 gene. Bestrophin's function is still unknown, but data suggests that it is a chloride channel that plays a role in generating the altered EOG in Best disease patients. In addition, Bestrophin is a useful biochemical and histological marker of RPE (retinal pigment epithelial cells) cells.
Related PathwayIon Channels: OtherTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western Blot: Bestrophin Antibody (E6-6) - Western blot detection of Bestrophin (68 kDa) from human RPE cell lysate.
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