Home Antibody All anti-TIMP1 antibodies
Also for TIMP1 (NM_003254)
|Peptide with sequence C-NSLSLAQRRGFTKTY, from the internal region of the protein sequence according to NP_003245.1.|
|Test: Human. Expected from seq similarity: Human, Dog,
||Lot dependent; please refer to CoA along with shipment
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
|Homo sapiens TIMP metallopeptidase inhibitor 1 (TIMP1)|
|CLGI; EPA; EPO; HCI; TIMP|
Entrez Gene 7076 Human
Entrez Gene 403816 Dog
|This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq]. |
|Secreted ProteinDruggable Genome |
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TA309545 (0.1µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.