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Home Antibody All anti-ATP2B1 antibodies

Anti-ATP2B1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA309535 Goat Polyclonal Antibody against ATP2B1 (aa312-327) 100ug $325 3-7 Days
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OriGene Data

ImmunogenPeptide with sequence C-KQDGAIENRNKAKAQD, from the internal region of the protein sequence according to NP_001001323.1; NP_001673.2.
Clone Name Isotype
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 0.03-1ug/ml
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Reference Data

Target NameHomo sapiens ATPase, Ca++ transporting, plasma membrane 1 (ATP2B1), transcript variant 2
Alternative NamePMCA1; PMCA1kb
Database LinkNP_001673
Entrez Gene 490 Human
Entrez Gene 67972 Mouse
Entrez Gene 29598 Rat
Entrez Gene 403480 Dog
FunctionThe protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].
Related PathwayTransmembraneDruggable Genome Calcium signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA309535 (0.03µg/ml) staining of HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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