Home Antibody All anti-Cyp1a2 antibodies
Also for Cyp1a2 (NM_009993)
|Peptide with sequence C-HSENYKDNGGLIPEEK, from the internal region of the protein sequence according to NP_034123.1.|
||Lot dependent; please refer to CoA along with shipment
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
|Mus musculus cytochrome P450, family 1, subfamily a, polypeptide 2 (Cyp1a2)|
|CP12; Cyp1a1; P450-3|
|This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq]. |
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TA309532 (1µg/ml) staining of fetal Mouse Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.