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Home Antibody All anti-MTHFR antibodies

Anti-MTHFR Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309530
  • Goat Polyclonal Antibody against MTHFR (aa369-383)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416960) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for MTHFR (NM_005957)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-SRPKSYIYRTQEWDE, from the internal region of the protein sequence according to NP_005948.3.
Clone Name Isotype
Species ReactivityTest: Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 0.3-1ug/ml
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Reference Data

Target NameHomo sapiens methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR)
Alternative NameOTTHUMP00000002367; OTTHUMP00000002368; methylenetetrahydrofolate reductase intermediate form; 5,10-methylenetetrahydrofolate reductase (NADPH)
Database LinkNP_005948
Entrez Gene 4524 Human
Entrez Gene 17769 Mouse
Entrez Gene 362657 Rat
Entrez Gene 478230 Dog
FunctionThe protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Related PathwayDruggable Genome One carbon pool by folateMethane metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA309530 (0.3µg/ml) staining of NIH3T3 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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