Home Antibody All anti-MTHFR antibodies
Also for MTHFR (NM_005957)
|Peptide with sequence C-SRPKSYIYRTQEWDE, from the internal region of the protein sequence according to NP_005948.3.|
|Human, Mouse, Rat, Dog, porcine, Cow
||Lot dependent; please refer to CoA along with shipment
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
|Homo sapiens methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR)|
|OTTHUMP00000002367; OTTHUMP00000002368; methylenetetrahydrofolate reductase intermediate form; 5,10-methylenetetrahydrofolate reductase (NADPH)|
|The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency. |
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TA309530 (0.3µg/ml) staining of NIH3T3 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.