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Home Antibody All anti-UBB antibodies

Anti-UBB Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA309498 Rabbit Polyclonal anti-UBB Antibody 50ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenNative bovine Ubiquitin, conjugated to KLH
Clone Name Isotype
Species ReactivityHuman, Monkey, Mouse, Rat, Hamster, Rabbit, Guinea porcine, Bovine, porcine, dog, Sheep, Chicken, Xenopus, Drosophila Concentration1mg/mL
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB, IP
BufferPBS pH7.4, 50% glycerol

Reference Data

Target NameHomo sapiens ubiquitin B (UBB), transcript variant 1
Alternative NameHEL-S-50; HEL-S-50
Database LinkNP_061828
Entrez Gene 7314 Human
Entrez Gene 22187 Mouse
Entrez Gene 192255 Rat
Entrez Gene 696110 Monkey
Entrez Gene 479513 Dog
FunctionThis gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq].
Related PathwayDruggable Genome Parkinson's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Western blot analysis of ubiquitinated proteins in HEK93 cells, using a dilution of anti-UBB.
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IHC Image
Immunohistochemistry analysis using Rabbit Anti-Ubiquitin Polyclonal Antibody. Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-Ubiquitin Polyclonal Antibody at 1:100000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT.
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IF Image
Ubiquitin visualized using anti-UBB, tested on Bouin's fixed paraffin-embedded backskin sections of transgenic mice.
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