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Anti-MAPK14 Antibody 9F12
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for MAPK14 (NM_001315)
|Full length recombinant protein expressed in E.coli cells.|
||WB, IP, ELISA
|PBS, 50% glycerol, 0.09% sodium azide|
|Homo sapiens mitogen-activated protein kinase 14 (MAPK14), transcript variant 1|
|CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; p38; p38ALPHA; PRKM14; PRKM15; RK; SAPK2A|
|The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]. |
EGFR1 Signaling Pathway
MAPK signaling pathway
Senescence and Autophagy
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
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Multi-blot analysis of p38Alpha MAPKinase in cell lysate from 12 human cancer cell lines using a 1:1000 dilution of anti-MAPK14.