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Home Antibody All anti-MAPK14 antibodies

Anti-MAPK14 Antibody 9F12

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309452
  • Mouse Monoclonal anti-MAPK14 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400523) , 20ug
100ug $325 3-7 Days
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WB(1)
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Also for MAPK14 (NM_001315)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length recombinant protein expressed in E.coli cells.
Clone Name9F12 IsotypeIgG1
Species ReactivityHuman, Rat Concentration250ug/mL
Guaranteed Application *WB Suggested DilutionsWB, IP, ELISA
BufferPBS, 50% glycerol, 0.09% sodium azide

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase 14 (MAPK14), transcript variant 1
Alternative NameCSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; p38; p38ALPHA; PRKM14; PRKM15; RK; SAPK2A
Database LinkNP_001306
FunctionThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq].
Related Pathway
EGFR1 Signaling Pathway
Hemostasis
MAPK signaling pathway
Senescence and Autophagy
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway

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WB Image
Multi-blot analysis of p38Alpha MAPKinase in cell lysate from 12 human cancer cell lines using a 1:1000 dilution of anti-MAPK14.

 

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