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Anti-KCNA3 Antibody S23-27
Also for KCNA3 (NM_002232)
|Synthetic peptide amino acids 485- 506 (Cytoplasmic C-terminus) of rat Kv1.3 (GGMNHSAFPQTPFKTGNSYATC),accession number P15384.|
|Human, Mouse, Rat
||WB, IHC, IP
|PBS pH7.2, 50% glycerol|
|Homo sapiens potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3)|
|HGK5; HLK3; HPCN3; HUKIII; KV1.3; MK3; PCN3|
|Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq]. |
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IHC analysis of Kv1.3 in frozen sections of mouse brain extract using anti-KCNA3.