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Home Antibody All anti-KCNQ4 antibodies

Anti-KCNQ4 Antibody S43-6

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309408
  • Mouse Monoclonal anti-KCNQ4 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417828) , 20ug
100ug $325 3-7 Days
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OriGene Data

ImmunogenFusion protein amino acids 2-77 of human KCNQ4, accession number P56696
Clone NameS43-6 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application *WB Suggested DilutionsWB, IP, ICC
BufferPBS, 50% glycerol

Reference Data

Target NameHomo sapiens potassium voltage-gated channel, KQT-like subfamily, member 4 (KCNQ4), transcript variant 1
Alternative NameDFNA2; DFNA2A; KV7.4
Database LinkNP_004691
FunctionThe protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

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WB Image
Western blot analysis of KCNQ4 in rat tissue lysates using a 1:1000 dilution of SMC-309.

 

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