Home Antibody All anti-KCNQ2 antibodies
Anti-KCNQ2 Antibody S26A-23
Also for KCNQ2 (BC000699)
|Fusion protein amino acids 1-59 of human KCNQ2, accession number O43526|
|Human, Mouse, Rat
||WB, IP, IHC
|PBS, 50% glycerol|
|Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 2, transcript variant 5 (cDNA clone MGC:2034 IMAGE:3349625), complete cds |
|KVEBN1;BFNC; EBN; EBN1; ENB1; HNSPC; KCNA11; KV7.2; neuroblastoma-specific potassium channel protein; potassium voltage-gated channel KQT-like protein 2; potassium voltage-gated channel, KQT-like subfamily, member 2|
|The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq]. |
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IHC analysis of KCNQ2 in frozen sections of mouse brain using SMC-308.