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Home Antibody All anti-DUX4L1 antibodies

Anti-DUX4L1 Antibody P2B1


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA309324 Mouse Mononclonal anti-DUX4 Antibody 100ug $325 In Stock
LC409695 DUX4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenC-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
Clone NameP2B1 IsotypeIgG1
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB, IF, IHC
BufferTBS pH7.4, 50% glycerol

Reference Data

Target NameHomo sapiens double homeobox 4 (DUX4)
Alternative NameDUX10
Database LinkNP_149418
Entrez Gene 22947 Human
FunctionThis gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that contains two homeoboxes; the repeat-array and ORF is conserved in other mammals. There was no evidence for transcription from standard cDNA libraries however RTPCR and in-vitro expression experiments indicate that the ORF is transcribed and the encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the microsatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot using anti-DUX4 N-terminus mouse monoclonal on C2C12 cells transfected with pCS2+DUX4, which contains an additional upstream start site.

IF Image
Immmunofluorescence staining using mouse monoclonal anti-DUX4 N-terminus on C2C12 myoblasts transfected with pCS2+DUX4. Counter-stained with DAPI for nuclei.


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