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Home Antibody All anti-CACNB4 antibodies

Anti-CACNB4 Antibody S10-7

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309312
  • Mouse Monoclonal anti-CACNB4 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400240) , 20ug
100ug $325 3-7 Days
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WB(1)
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Also for CACNB4 (NM_000726)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide amino acids 458-474 of rat CavB4
Clone NameS10-7 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application *WB Suggested DilutionsWB, IP, IHC
BufferPBS pH7.4, 50% glycerol

Reference Data

Target NameHomo sapiens calcium channel, voltage-dependent, beta 4 subunit (CACNB4), transcript variant 2
Alternative NameCAB4; CACNLB4; EA5; EIG9; EJM; EJM4; EJM6
Database LinkNP_000717
FunctionThis gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway
MAPK signaling pathway

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WB Image
Western blot analysis of CavBeta4 in T-CHO lysates using a 1:1000 dilution of SMC-318.

 

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