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Home Antibody All anti-NEFL antibodies

Anti-NEFL Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309179
  • Chicken Anti-Neurofilament NF-L ck Antibody
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenPreparation of bovine spinal cord NF-L
Clone Name IsotypeIgY
Species Reactivityrat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:10,000, IF: 1:5,000
Buffertotal IgY fraction in PBS + 10 mM NaN3.
Purification Total IgY fraction

Reference Data

Target NameRattus norvegicus neurofilament, light polypeptide (Nefl)
Alternative NameNF-L; Nfl
Database LinkNP_113971
Entrez Gene 83613 Rat
FunctionNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq].
Related Pathway

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WB Image
Western blot of rat cortex lysate showing specific immunolableing of the ~ 68k NF-L protein.

 

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