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Anti-MAP2K1 PHOSPHO Antibody
Also for MAP2K1 (NM_008927)
|Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser218/222 conjugated to KLH|
||Lot dependent; please refer to CoA along with shipment
|100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
|Mus musculus mitogen-activated protein kinase kinase 1 (Map2k1)|
|MAPKK1; Mek1; MEKK1; Prkmk1|
Entrez Gene 26395 Mouse
|The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq]. |
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Western Blot of NIH 3T3 cell lysates showing specific immunolabeling of the ~45k MEK 1/2 protein phosphorylated at Ser218 and Ser222. The cells were either serum starved (Control) or incubated in the presence of serum (Serum). Immunolabeling of an additional band at ~95k was also observed.