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Home Antibody All anti-MAP2K1 antibodies

Anti-MAP2K1 PHOSPHO Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA309166 Rabbit Anti-MEK1/2 (Ser218,222) Antibody (Phospho-Specific) 100ul $325 3-7 Days
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OriGene Data

ImmunogenSynthetic phospho-peptide corresponding to amino acid residues surrounding Ser218/222 conjugated to KLH
Clone Name IsotypeIgG
Species Reactivitymouse ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000
Predicted MW Explanation 45 kDa
Buffer100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification Affinity Purified

Reference Data

Target NameMus musculus mitogen-activated protein kinase kinase 1 (Map2k1)
Alternative NameMAPKK1; Mek1; MEKK1; Prkmk1
Database LinkNP_032953
Entrez Gene 26395 Mouse
FunctionThe protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western Blot of NIH 3T3 cell lysates showing specific immunolabeling of the ~45k MEK 1/2 protein phosphorylated at Ser218 and Ser222. The cells were either serum starved (Control) or incubated in the presence of serum (Serum). Immunolabeling of an additional band at ~95k was also observed.


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