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Anti-FTO Antibody 5-2H10
Also for FTO (NM_001080432)
|Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH|
|human, mouse, rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1,000, IF: 1:100
|100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
|Protein G purified
|Homo sapiens fat mass and obesity associated (FTO)|
|This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq]. |
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Western blot of rat testes lysate showing specific immunolabeling of the ~ 58k Fto protein.