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Home Antibody All anti-SLC6A3 antibodies

Anti-SLC6A3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309112
  • Rabbit Anti-Dopamine Transporter, Extracellular Loop 2, Human Antibody
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to amino acid residues from the extracellular loop 2 region conjugated to KLH
Clone Name IsotypeIgG
Species Reactivityhuman, monkey ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:100, IHC: 1:1000
Predicted MW Explanation 88 kDa
Buffer100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification Affinity Purified

Reference Data

Target NameHomo sapiens solute carrier family 6 (neurotransmitter transporter), member 3 (SLC6A3)
Alternative NameDAT; DAT1; PKDYS
Database LinkNP_001035
Entrez Gene 6531 Human
Entrez Gene 574143 Monkey
FunctionThis gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.
Related PathwayTransmembraneDruggable Genome Parkinson's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot of human caudate lysate showing specific immunolabeling of the ~88k DAT protein.

 

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