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Home Antibody All anti-ATF2 antibodies

Anti-ATF2 PHOSPHO Antibody

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SKU Description Amount Price Availability*  
TA309084 Rabbit Anti-ATF2 (Ser490,498) Antibody (Phospho-Specific) 100ul $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic phospho-peptide corresponding to amino acid residues surrounding Ser490/498 conjugated to KLH
Clone Name IsotypeIgG
Species Reactivityhuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000, IHC: 1:1000
Predicted MW Explanation 74 kDa
Buffer100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification Affinity Purified

Reference Data

Target NameHomo sapiens activating transcription factor 2 (ATF2), transcript variant 1
Alternative NameCRE-BP1; CREB-2; CREB2; HB16; TREB7
Database LinkNP_001871
Entrez Gene 1386 Human
FunctionThis gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq].
Related PathwayTranscription FactorsDruggable Genome MAPK signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot of human melanoma cells incubated with varying doses of the radiomimetic drug NCS showing specific immuno-labeling of the ~74k ATF2 protein phosphorylated at Ser490 and Ser498.
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