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Home Antibody All anti-FGD4 antibodies

Anti-FGD4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309049
  • Rabbit polyclonal antibody to FGD4 (FYVE, RhoGEF and PH domain containing 4)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403384) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for FGD4 (NM_139241)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 49 and 297 of FGD4
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:100; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens FYVE, RhoGEF and PH domain containing 4 (FGD4)
Alternative NameCMT4H; FRABP; ZFYVE6
Database LinkNP_640334
FunctionThis gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq]
Related Pathway
Signaling by GPCR

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WB Image
Sample (30 ug of whole cell lysate) A: Molt-4 (anti-FGD4 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded SG xenograft, using FGD4(anti-FGD4 antibody) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using FGD4(anti-FGD4 antibody) antibody at 1:200 dilution.

 

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