Home All anti-UNC13B antibodies
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Also for UNC13B (NM_006377)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 680 and 927 of human UNC13B|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens unc-13 homolog B (C. elegans) (UNC13B)|
|MUNC13; UNC13; Unc13h2|
|This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: 293T (anti-UNC13B antibody diluted at 1:500)
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using UNC13B(anti-UNC13B antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of methanol-fixed HeLa, using UNC13B(anti-UNC13B antibody) antibody at 1:200 dilution.