Home Antibody All anti-FIG4 antibodies
Also for FIG4 (NM_014845)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 135 and 400 of FIG4|
||0.5~1.0 mg/ml (Lot Dependent)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae) (FIG4)|
|ALS11; CMT4J; dJ249I4.1; KIAA0274; SAC3; YVS|
|The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq]|
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A: HCT116 (anti-FIG4 antibody diluted at 1:1000)