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Home Antibody All anti-FIG4 antibodies

Anti-FIG4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308985
  • Rabbit polyclonal antibody to FIG4 (FIG4 homolog (S. cerevisiae))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC414969) , 20ug
100ul 325 In Stock
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WB(1)
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Also for FIG4 (NM_014845)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 135 and 400 of FIG4
Clone Name IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae) (FIG4)
Alternative NameALS11; CMT4J; dJ249I4.1; KIAA0274; SAC3; YVS
Database LinkNP_055660
FunctionThe protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq]
Related Pathway

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WB Image
A: HCT116 (anti-FIG4 antibody diluted at 1:1000)

 

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