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Home Antibody All anti-SUCLA2 antibodies

Anti-SUCLA2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308975
  • Rabbit Polyclonal antibody to SUCLA2 (succinate-CoA ligase, ADP-forming, beta subunit)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401267) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for SUCLA2 (NM_003850)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 138 and 386 of human SUCLA2
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:1000-1:20000; IHC:1:500; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens succinate-CoA ligase, ADP-forming, beta subunit (SUCLA2)
Alternative NameA-BETA; MTDPS5; SCS-betaA
Database LinkNP_003841
Entrez Gene 8803 Human
Entrez Gene 20916 Mouse
FunctionSuccinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq]
Related Pathway Citrate cycle (TCA cycle)Propanoate metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate) A: HepG2 B: Molt-4 (anti-SUCLA2 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using SUCLA2(anti-SUCLA2 antibody) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed A431, using SUCLA2(anti-SUCLA2 antibody) antibody at 1:200 dilution.

 

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