Anti-TP63 Antibody,

Also for TP63 (NM_001114982)

OriGene Data

Immunogen	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 125 and 385 of p63
Clone Name		Isotype	IgG
Species Reactivity	Human	Concentration	1mg/ml
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB:1:500-1:3000; IHC:1:100; IF:1:100-1:500;
Buffer	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification	Purified by antigen-affinity chromatography. (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens tumor protein p63 (TP63), transcript variant 6
Alternative Name	AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4;
Database Link	NP_001108454
Function	This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq]
Related Pathway

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WB Image

Sample(30 ug whole cell lysate) A:A431 (anti-TP63 antibody diluted at 1:500)

IHC Image

Immunohistochemical analysis of paraffin-embedded SCC4 xenograft, using p63(anti-TP63 antibody) antibody at 1:100 dilution.

IF Image

Immunofluorescence analysis of paraformaldehyde-fixed A431, using p63 (anti-TP63 antibody) antibody at 1:200 dilution.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
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DyLight® 550
DyLight® 594
DyLight® 633

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Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-TP63 Antibody

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data