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Home Antibody All anti-KLRC4 antibodies

Anti-KLRC4 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308966 Rabbit polyclonal antibody to KLRC4 (killer cell lectin-like receptor subfamily C, member 4) 100ul $325 3-7 Days
LC402263 KLRC4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 1 and 45 of KLRC4 (Uniprot ID#O43908)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Chimpanzee) Concentration0.15mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 18kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Chimpanzee (100%)

Reference Data

Target NameHomo sapiens killer cell lectin-like receptor subfamily C, member 4 (KLRC4)
Alternative NameNKG2-F; NKG2F
Database LinkNP_038459
Entrez Gene 8302 Human
FunctionNatural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC4 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The 3' end of the KLRC4 transcript includes the first non-coding exon found at the 5' end of the adjacent D12S2489E gene transcript. [provided by RefSeq]
Related PathwayTransmembrane Antigen processing and presentation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample(30 ug of whole cell lysate). A:293T. 12% SDS PAGE. TA308966 diluted at 1:1000
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