Home Antibody All anti-KLRC4 antibodies
Also for KLRC4 (NM_013431)
|Synthetic peptide corresponding to a region within amino acids 1 and 45 of KLRC4 (Uniprot ID#O43908)|
|Human (Predicted: Chimpanzee)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Chimpanzee (100%)
|Homo sapiens killer cell lectin-like receptor subfamily C, member 4 (KLRC4)|
Entrez Gene 8302 Human
|Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC4 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The 3' end of the KLRC4 transcript includes the first non-coding exon found at the 5' end of the adjacent D12S2489E gene transcript. [provided by RefSeq]|
|Transmembrane Antigen processing and presentation|
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Sample(30 ug of whole cell lysate). A:293T. 12% SDS PAGE. TA308966 diluted at 1:1000