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Home Antibody All anti-PSMA6 antibodies

Anti-PSMA6 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308942
  • Rabbit Polyclonal antibody to Proteasome 20S alpha 6 (proteasome (prosome, macropain) subunit, alpha type, 6)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419119) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
IF(1)
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Also for PSMA6 (NM_002791)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment contain a sequence corresponding to a region within amino acids 1 and 234 of Proteasome 20S alpha 6 (Uniprot ID#P60900)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Rat, Sheep, Rhesus Monkey, Chimpanzee, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 27kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (100%), Sheep (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens proteasome (prosome, macropain) subunit, alpha type, 6 (PSMA6), transcript variant 1
Alternative NameIOTA; p27K; PROS27
Database LinkNP_002782
Entrez Gene 5687 Human
Entrez Gene 26443 Mouse
Entrez Gene 29673 Rat
Entrez Gene 699631 Monkey
FunctionThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq]
Related PathwayProteaseStem cell - PluripotencyDruggable Genome Proteasome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug whole cell lysate). A:Hep G2 . 7.5% SDS PAGE. TA308942 diluted at 1:500
WB Image
Sample (50 ug of whole cell lysate). A: Mouse brain. 12% SDS PAGE. TA308942 diluted at 1:1000.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using 20S Proteasome alpha 6(TA308942) antibody at 1:200 dilution.

 

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