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Home Antibody All anti-PROC antibodies

Anti-PROC Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308939 Rabbit polyclonal antibody to Protein C (protein C (inactivator of coagulation factors Va and VIIIa)) 100ul $325 3-7 Days
LC400117 PROC HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 145 and 461 of Protein C (Uniprot ID#P04070)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Dog) Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 52kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Dog (82%)

Reference Data

Target NameHomo sapiens protein C (inactivator of coagulation factors Va and VIIIa) (PROC)
Alternative NameAPC; PC; PROC1; THPH3; THPH4
Database LinkNP_000303
Entrez Gene 5624 Human
FunctionThe PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930; MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5; MIM 612309) and VIII (F8; see MIM 306700). Protein S (PROS1; MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM]
Related PathwayProteaseDruggable Genome Complement and coagulation cascades

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Molt-4 . 10% SDS PAGE. TA308939 diluted at 1:3000
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