Home Antibody All anti-PDE4B antibodies
Also for PDE4B (NM_001037341)
|Recombinant fragment corresponding to a region within amino acids 489 and 736 of PDE4B (Uniprot ID#Q07343)|
|Human (Predicted: Rhesus Monkey)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Rhesus Monkey (100%)
|Homo sapiens phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant d|
|DPDE4; PDE4B5; PDEIVB|
Entrez Gene 5142 Human
Entrez Gene 699309 Monkey
|This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Druggable Genome Purine metabolismProgesterone-mediated oocyte maturation|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Sample (30 ug of whole cell lysate)Â . A: NT2D1. B:Â PC-3. 7.5% SDS PAGEÂ . TA308931 diluted at 1:1000. Â
PDE4B antibody detects PDE4B protein by western blot analysis. Whole cell extracts (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with PDE4B antibody (TA308931) diluted by 1:1000.