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Home Antibody All anti-MMP2 antibodies

Anti-MMP2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308925
  • Rabbit Polyclonal antibody to MMP2 (matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase))
100ul 325 3-7 Days
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WB(2)
IF(1)
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Also for MMP2 (NM_001127891)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 193 and 545 of Human MMP2
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.55mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (MMP2), transcript variant 2
Alternative NameCLG4; CLG4A; MMP-II; MONA; TBE-1
Database LinkNP_001121363
FunctionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related Pathway

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WB Image
A: HepG2 (anti-MMP2 antibody diluted at 1:1000)
WB Image
A: Mouse brain (anti-MMP2 antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using MMP2(anti-MMP2 antibody) antibody at 1:200 dilution.

 

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