OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-MMP2 antibodies

Anti-MMP2 Antibody

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308925
  • Rabbit Polyclonal antibody to MMP2 (matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase))
100ul $325 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

spacer
WB(2)
IHC(1)
IF(1)
spacer
Also for MMP2 (NM_001127891)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 193 and 575 of MMP2 (Uniprot ID#P08253)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Xenopus laevis, Bovine) Concentration0.55mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 74kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Xenopus laevis (81%), Bovine (94%)

Reference Data

Target NameHomo sapiens matrix metallopeptidase 2 (MMP2), transcript variant 2
Alternative NameCLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1
Database LinkNP_001121363
Entrez Gene 4313 Human
Entrez Gene 17390 Mouse
FunctionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related PathwayProteaseDruggable Genome Leukocyte transendothelial migrationGnRH signaling pathwayPathways in cancerBladder cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308925 diluted at 1:1000.
spacer
MMP2 antibody detects MMP2 protein by western blot analysis. Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with MMP2 antibody (TA308925) diluted by 1:3000.
spacer
Immunohistochemical analysis of paraffin-embedded U251 xenograft, using MMP2(TA308925) antibody at 1:500 dilution.
spacer
Immunofluorescence analysis of methanol-fixed HeLa, using MMP2(TA308925) antibody at 1:200 dilution.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title