Home Antibody All anti-H2AFZ antibodies
Also for H2AFZ (NM_002106)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 65 and 128 of Human H2AFZ|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens H2A histone family, member Z (H2AFZ)|
|H2A.z; H2A.Z-1; H2A/z; H2AZ|
Entrez Gene 3015 Human
|Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq]|
|Druggable Genome Systemic lupus erythematosus|
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Sample(30 ug of whole cell lysate) A:MOLT4 B:Raji (anti-H2AFZ antibody diluted at 1:3000
Immunohistochemical analysis of paraffin-embedded ES-2 xenograft, using Histone H2A.Z(anti-H2AFZ antibody) antibody at 1:100 dilution.