Home Antibody All anti-GSTM1 antibodies
Also for GSTM1 (NM_000561)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 159 of Human GSTM1|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:100; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens glutathione S-transferase mu 1 (GSTM1), transcript variant 1|
|GST1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MU; MU-1|
Entrez Gene 2944 Human
Entrez Gene 14862 Mouse
|Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq]|
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A: Hela (anti-GSTM1 antibody diluted at 1:1000)
A: mouse brain (anti-GSTM1 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded NCI-N87 xenograft, using GSTM1(anti-GSTM1 antibody) antibody at 1:100 dilution.
Immunofluorescence analysis of methanol-fixed HeLa, using GSTM1(anti-GSTM1 antibody) antibody at 1:200 dilution.