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Home Antibody All anti-GSTM1 antibodies

Anti-GSTM1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308892 Rabbit Polyclonal antibody to GSTM1 (glutathione S-transferase mu 1) 100ul $325 In Stock
LC425001 GSTM1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment contain a sequence corresponding to a region within amino acids 1 and 189 of GSTM1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Human) Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 21kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Human (100%)

Reference Data

Target Nameglutathione S-transferase mu 1
Alternative NameGST1|GSTM1-1|GSTM1a-1a|GSTM1b-1b|GTH4|GTM1|H-B|MU|MU-1
Database LinkNP_000552
Entrez Gene 2944 Human
Entrez Gene 14862 Mouse
FunctionCytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq]
Related PathwayDruggable Genome Glutathione metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
GSTM1 antibody detects protein by Western blot analysis. A. 50 ug mouse brain lysate/extract. 12 % SDS-PAGE. GSTM1 antibody (TA308892) dilution: 1:1000

WB Image
GSTM1 antibody detects GSTM1 protein by Western blot analysis. A. 50 ug rat liver lysate/extract. 12 % SDS-PAGE. GSTM1 antibody (TA308892) dilution: 1:2000


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