Home Antibody All anti-F10 antibodies
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 33 and 282 of Human F10|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens coagulation factor X (F10)|
|This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: HepG2 (anti-F10 antibody diluted at 1:5000)
Immunofluorescence analysis of methanol-fixed HeLa, using Factor X(anti-F10 antibody) antibody at 1:200 dilution.