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Also for CAV2 (NM_001233)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of Human CAV2|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:200;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens caveolin 2 (CAV2), transcript variant 1|
|The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript. [provided by RefSeq]|
EGFR1 Signaling Pathway
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A: A549 (anti-CAV2 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded FaDu xenograft, using Caveolin 2(anti-CAV2 antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using Caveolin 2(anti-CAV2 antibody) antibody at 1:200 dilution.