Home Antibody All anti-BCL2L1 antibodies
Also for BCL2L1 (NM_001191)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 89 and 151 of Human BCL2L1|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:100; IF:1:100-1:200;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens BCL2-like 1 (BCL2L1), transcript variant 2|
|Bcl-X; bcl-xL; BCL-XL/S; bcl-xS; BCL2L; BCLX; BCLXL; BCLXS; PPP1R52|
|The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq]|
Jak-STAT signaling pathway
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A: HeLa (anti-BCL2L1 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded DLD1 xenograft, using BCL-x(anti-BCL2L1 antibody) antibody at 1:100 dilution.
Immunofluorescence analysis of methanol-fixed A431, using BCL-x(anti-BCL2L1 antibody) antibody at 1:200 dilution.