Home Antibody All anti-APP antibodies
Also for APP (NM_001136131)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 602 and 757 of Human APP|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens amyloid beta (A4) precursor protein (APP), transcript variant 7|
|AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2|
|This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]|
Delta-Notch Signaling Pathway
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Sample(30 ug of whole cell lysate) A:HepG2 (anti-APP antibody diluted at 1:1500
Immunohistochemical analysis of paraffin-embedded Tonsil, plasma cells, using beta A4 Amyloid(anti-APP antibody) antibody(10 ?g/ml).