Home Antibody All anti-APP antibodies
Also for APP (NM_001136131)
|Recombinant fragment corresponding to a region within amino acids 602 and 770 of beta Amyloid (Uniprot ID#P05067)|
|Human, Mouse (Predicted: Dog, Pig, Chimpanzee, Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Dog (100%), Pig (100%), Chimpanzee (100%), Bovine (100%)
|Homo sapiens amyloid beta (A4) precursor protein (APP), transcript variant 7|
|AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2|
Entrez Gene 351 Human
Entrez Gene 11820 Mouse
Entrez Gene 403407 Dog
|This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]|
|TransmembraneDruggable Genome Alzheimer's disease|
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Sample(30 ug of whole cell lysate). A:Hep G2. 7.5% SDS PAGE. TA308848 diluted at 1:1500
Sample (30 ug of whole cell lysate). A:NIH-3T3 7.5% SDS PAGE. TA308848 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Tonsil, plasma cells, using beta A4 Amyloid(TA308848) antibody(10 ug/ml).
beta Amyloid antibody [C2C3], C-term detects APP protein at cytoplasm by confocal immunofluorescent analysis. Sample: A431 cells were fixed in ice-cold MeOH for 5 min. Green: APP protein stained by beta Amyloid antibody [C2C3], C-term (TA308848) diluted a