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Home Antibody All anti-AGT antibodies

Anti-AGT Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308844
  • Rabbit Polyclonal antibody to Angiotensinogen (angiotensinogen (serpin peptidase inhibitor, clade A, member 8))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400005) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for AGT (NM_000029)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 476 of Angiotensinogen (Uniprot ID#P01019)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 53kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT)
Alternative NameANHU; SERPINA8
Database LinkNP_000020
Entrez Gene 183 Human
FunctionThe protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq]
Related PathwaySecreted ProteinDruggable Genome Renin-angiotensin system

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug whole cell lysate). A:Hep G2 . 10% SDS PAGE. TA308844 diluted at 1:1000
IHC Image
Immunohistochemical analysis of paraffin-embedded Hepatocellular carcinoma Huh7 xenograft, using AGT(TA308844) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed HepG2, using Angiotensinogen(TA308844) antibody at 1:200 dilution.

 

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