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Home Antibody All anti-XRCC5 antibodies

Anti-XRCC5 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308827
  • Rabbit polyclonal antibody to Ku80 (XRCC5) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC412062) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IP(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 315 and 593 of Ku80 (Uniprot ID#P13010)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1.01mg/ml
Guaranteed Application *WB, IHC, IF, IP Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 83kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5)
Alternative NameKARP-1; KARP1; KU80; Ku86; KUB2; NFIV
Database LinkNP_066964
Entrez Gene 7520 Human
FunctionThe protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
Related PathwayStem cell - PluripotencyDruggable Genome Non-homologous end-joining

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Ku80 antibody [N3C2], Internal detects XRCC5 protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug A431 whole cell lysate/extract. C. 30 ug HeLa whole cell lysate/extract. D. 30 ug HepG2 whole cell lysate/extract. 7.5 % SDS-P
IHC Image
Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using Ku80 (XRCC5)(TA308827) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using Ku80 (XRCC5)(TA308827) antibody at 1:200 dilution.
IP Image
Ku80(XRCC5) antibody immunoprecipitates Ku80 protein in IP experiments. IP Sample: 1000 ug HeLa whole cell lysate/extract A. 40 ug HeLa whole cell lysate/extract B. Control with 2.5 ug of preimmune rabbit IgG C. Immunoprecipitation of Ku80 protein by 2.5

 

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