Home Antibody All anti-DDB1 antibodies
Also for DDB1 (NM_001923)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 749 and 1123 of DDB1|
|WB, IHC, IF
||WB:1:1000-1:10000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens damage-specific DNA binding protein 1, 127kDa (DDB1)|
|DDBA; UV-DDB1; XAP1; XPCE; XPE; XPE-BF|
|This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: HepG2 (anti-DDB1 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft , using DDB1(anti-DDB1 antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using DDB1(anti-DDB1 antibody) antibody at 1:200 dilution.