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Home Antibody All anti-SAFB antibodies

Anti-SAFB Antibody

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SKU Description Amount Price Availability*  
TA308810 Rabbit polyclonal antibody to Scaffold attachment factor B1 (scaffold attachment factor B) 100ul $325 3-7 Days

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(4)
IF(1)

OriGene Data

ImmunogenRecombinant fragment contain a sequence corresponding to a region within amino acids 476 and 695 of SAFB (Uniprot ID#Q15424)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 103kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Bovine (87%)

Reference Data

Target NameHomo sapiens scaffold attachment factor B (SAFB), transcript variant 3
Alternative NameHAP; HET; SAF-B1; SAFB1
Database LinkNP_002958
Entrez Gene 6294 Human
FunctionThis gene encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis. [provided by RefSeq]
Related PathwayTranscription FactorsDruggable Genome

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Sample (30 ug of whole cell lysate). A: A431 . B: Hep G2 . 7.5% SDS PAGE. TA308810 diluted at 1:1000.
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Scaffold attachment factor B1 antibody detects Scaffold attachment factor B1 protein at nucleus on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. Scaffold attachment factor B1 antibody (TA308810) dilution: 1:
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Scaffold attachment factor B1 antibody detects Scaffold attachment factor B1 protein at nucleus on mouse intestine by immunohistochemical analysis. Sample: Paraffin-embedded mouse esophagus. Scaffold attachment factor B1 antibody (TA308810) dilution: 1:50
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Scaffold attachment factor B1 antibody detects Scaffold attachment factor B1 protein at nucleus on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. Scaffold attachment factor B1 antibody (TA308810) dilution: 1:500
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Scaffold attachment factor B1 antibody detects Scaffold attachment factor B1 protein at nucleus on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. Scaffold attachment factor B1 antibody (TA308810) dilution: 1:500.
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Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Scaffold attachment factor B1(TA308810) antibody at 1:100 dilution.
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