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Home Antibody All anti-DUSP8 antibodies

Anti-DUSP8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308797
  • Rabbit Polyclonal antibody to DUSP8 (dual specificity phosphatase 8)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417999) , 20ug
100ul 325
$292
3-7 Days
Add to Shopping Cart
WB(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 1 and 14 of Human DUSP8
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.72mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens dual specificity phosphatase 8 (DUSP8)
Alternative NameC11orf81; HB5; HVH-5; HVH8
Database LinkNP_004411
FunctionThe protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq]
Related Pathway
MAPK signaling pathway

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WB Image
Sample(30 ug of whole cell lysate) A:Raji (anti-DUSP8 antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using DUSP8(anti-DUSP8 antibody) antibody at 1:200 dilution.

 

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