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Also for ANXA7 (NM_004034)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 122 and 429 of Human ANXA7|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens annexin A7 (ANXA7), transcript variant 2|
|ANX7; SNX; SYNEXIN|
|Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq]|
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Sample(30 ug of whole cell lysate) A:293T B:A431 (anti-ANXA7 antibody diluted at 1:2000
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using ANXA7(anti-ANXA7 antibody) antibody at 1:100 dilution.