Home Antibody All anti-RACGAP1 antibodies
Also for RACGAP1 (NM_001126104)
|Recombinant fragment corresponding to a region within amino acids 1 and 202 of RACGAP1 (Uniprot ID#Q9H0H5)|
|Human, Mouse (Predicted: Rat)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Rat (84%)
|Homo sapiens Rac GTPase activating protein 1 (RACGAP1), transcript variant 3|
|CYK4; HsCYK-4; ID-GAP; MgcRacGAP|
Entrez Gene 29127 Human
Entrez Gene 26934 Mouse
Entrez Gene 315298 Rat
|Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM]|
|Druggable Genome |
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Sample (50 ug of whole cell lysate). A: mouse heart. 7.5% SDS PAGE. TA308788 diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: A431 . B: Raji. 7.5% SDS PAGE. TA308788 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded H1299 xenograft , using RACGAP1(TA308788) antibody at 1:500 dilution.
Immunohistochemical analysis of paraffin-embedded Hepatoma, using RACGAP1(TA308788) antibody at 1:500 dilution.
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed A431, using RACGAP1(TA308788) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.