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Home Antibody All anti-RACGAP1 antibodies

Anti-RACGAP1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308788 Rabbit Polyclonal antibody to RACGAP1 (Rac GTPase activating protein 1) 100ul $325 In Stock
LC426646 RACGAP1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(2)
IHC(2)
IF(1)
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Also for RACGAP1 (NM_001126104)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 202 of RACGAP1 (Uniprot ID#Q9H0H5)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Rat) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 71kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (84%)

Reference Data

Target NameHomo sapiens Rac GTPase activating protein 1 (RACGAP1), transcript variant 3
Alternative NameCYK4; HsCYK-4; ID-GAP; MgcRacGAP
Database LinkNP_001119576
Entrez Gene 29127 Human
Entrez Gene 26934 Mouse
Entrez Gene 315298 Rat
FunctionRho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (50 ug of whole cell lysate). A: mouse heart. 7.5% SDS PAGE. TA308788 diluted at 1:1000.
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Sample (30 ug of whole cell lysate). A: A431 . B: Raji. 7.5% SDS PAGE. TA308788 diluted at 1:1000.
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Immunohistochemical analysis of paraffin-embedded H1299 xenograft , using RACGAP1(TA308788) antibody at 1:500 dilution.
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Immunohistochemical analysis of paraffin-embedded Hepatoma, using RACGAP1(TA308788) antibody at 1:500 dilution.
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Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed A431, using RACGAP1(TA308788) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.
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