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Home Antibody All anti-EIF4G2 antibodies

Anti-EIF4G2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308779 Rabbit Polyclonal antibody to DAP5 (eukaryotic translation initiation factor 4 gamma, 2) 100ul $325 3-7 Days
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OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 194 of DAP5
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Rat, Rabbit, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 102kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (100%), Rabbit (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2), transcript variant 2
Alternative NameAAG1; DAP5; NAT1; P97
Database LinkNP_001036024
Entrez Gene 1982 Human
Entrez Gene 13690 Mouse
Entrez Gene 361628 Rat
FunctionTranslation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq]
Related PathwayTranscription Factors Viral myocarditis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (50 ug of whole cell lysate). A: Mouse brain. 5% SDS PAGE. TA308779 diluted at 1:500.

WB Image
Sample(30 ug of whole cell lysate). A:A431. 7.5% SDS PAGE. TA308779 diluted at 1:1000

IHC Image
DAP5 antibody detects DAP5 protein at cytosol on mouse hind brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse hind brain. DAP5 antibody (TA308779) dilution: 1:500.

IHC Image
Immunohistochemical analysis of paraffin-embedded Skeletal Muscle , using DAP5(TA308779) antibody(10 ug/ml).

IHC Image
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using EIF4G2 (TA308779) antibody at 1:100 dilution.

IF Image
DAP5 antibody detects EIF4G2 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: EIF4G2 protein stained by DAP5 antibody (TA308779) diluted at 1:500. Blue: Hoechst 33343 staining.


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