Home Antibody All anti-IL1RN antibodies
Also for IL1RN (NM_000577)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 177 of Human IL1RN|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 3|
|DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4|
|The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]|
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Sample(30 ug whole cell lysate) A:MOLT4 (anti-IL1RN antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded PC3 xenograft, using IL1 Receptor antagonist(anti-IL1RN antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of methanol-fixed HeLa, using IL1ra antagonist (anti-IL1RN antibody) antibody at 1:200 dilution.