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Home Antibody All anti-APEX1 antibodies

Anti-APEX1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308774
  • Rabbit polyclonal antibody to APE1 (APEX nuclease (multifunctional DNA repair enzyme) 1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC429949) , 20ug
100ul $325 3-7 Days
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WB(1)
IF(1)
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Also for APEX1 (NM_080649)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of APE1
Clone Name IsotypeIgG
Species ReactivityHuman Concentration5.04mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Affinity purified by Protein A.

Reference Data

Target NameHomo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3
Alternative NameAPE; APE1; APEN; APEX; APX; HAP1; REF1
Database LinkNP_542380
FunctionApurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
A: A549 (anti-APEX1 antibody diluted at 1:3000
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using APE1(anti-APEX1 antibody) antibody at 1:200 dilution.

 

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