Home Antibody All anti-APEX1 antibodies
Also for APEX1 (NM_080649)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of APE1|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Affinity purified by Protein A. (Protein A or G Sepharose)
|Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 3|
|APE; APE1; APEN; APEX; APX; HAP1; REF1|
|Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]|
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A: A549 (anti-APEX1 antibody diluted at 1:3000
Immunofluorescence analysis of paraformaldehyde-fixed A431, using APE1(anti-APEX1 antibody) antibody at 1:200 dilution.