Home Antibody All anti-OGT antibodies
|Recombinant fragment corresponding to a region within amino acids 1 and 280 of O-GlcNAc transferase (Uniprot ID#O15294)|
|Human, Mouse (Predicted: Rat, Xenopus laevis, Xenopus Tropicalis, Pig, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Rat (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Pig (100%), Bovine (100%)
|Homo sapiens O-linked N-acetylglucosamine (GlcNAc) transferase (OGT), transcript variant 2|
Entrez Gene 8473 Human
Entrez Gene 108155 Mouse
Entrez Gene 26295 Rat
|O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]|
|Druggable Genome O-Glycan biosynthesisMetabolic pathways|
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Sample (50 ug of whole cell lysate). A: Mouse brain. 5% SDS PAGE. TA308773 diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: Hela. 7.5% SDS PAGE. TA308773 diluted at 1:1000
O-GlcNAc transferase antibody [N1N2], N-term detects O-GlcNAc transferase protein at cytosol on mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. O-GlcNAc transferase antibody [N1N2], N-term (TA308773) dilution:
O-GlcNAc transferase antibody [N1N2], N-term detects OGT protein at cytosol on U373 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded U373 xenograft. O-GlcNAc transferase antibody [N1N2], N-term (TA308773) dilution: 1:500.