Home Antibody All anti-RANBP1 antibodies
Also for RANBP1 (NM_002882)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 197 of Ran BP-1|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens RAN binding protein 1 (RANBP1), transcript variant 2|
|Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: HeLa S3 (anti-RANBP1 antibody diluted at 1:1000)
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Ran BP-1 (anti-RANBP1 antibody) antibody at 1:200 dilution.