Anti-UBQLN1 Antibody,

Also for UBQLN1 (NM_053067)

OriGene Data

Immunogen	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 64 and 315 of Ubiquilin-1
Clone Name		Isotype	IgG
Species Reactivity	Human	Concentration	1mg/ml
Guaranteed Application *	WB, IF	Suggested Dilutions	WB:1:500-1:3000; IF:1:100-1:200;
Buffer	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification	Purified by antigen-affinity chromatography. (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens ubiquilin 1 (UBQLN1), transcript variant 2
Alternative Name	DA41; DSK2; PLIC-1; UBQN; XDRP1
Database Link	NP_444295
Function	This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related Pathway

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WB Image

Sample (30 ug of whole cell lysate) A: 293T (anti-UBQLN1 antibody diluted at 1:1000)

IF Image

Immunofluorescence analysis of paraformaldehyde-fixed A549, using Ubiquilin-1(anti-UBQLN1 antibody) antibody at 1:200 dilution.

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Anti-UBQLN1 Antibody

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data