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Home Antibody All anti-UBQLN1 antibodies

Anti-UBQLN1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308768 Rabbit polyclonal antibody to Ubiquilin-1 (ubiquilin 1) 100ul $325 3-7 Days
LC409314 UBQLN1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for UBQLN1 (NM_053067)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 64 and 345 of Ubiquilin-1 (Uniprot ID#Q9UMX0)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 63kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (90%), Rat (90%), Bovine (95%)

Reference Data

Target NameHomo sapiens ubiquilin 1 (UBQLN1), transcript variant 2
Alternative NameDA41; DSK2; PLIC-1; UBQN; XDRP1
Database LinkNP_444295
Entrez Gene 29979 Human
Entrez Gene 56085 Mouse
Entrez Gene 114590 Rat
FunctionThis gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: 293T. 7.5% SDS PAGE. TA308768 diluted at 1:1000.

IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A549, using Ubiquilin-1(TA308768) antibody at 1:200 dilution.


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