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Home Antibody All anti-SCNN1A antibodies

Anti-SCNN1A Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308766 Rabbit polyclonal antibody to SCNN1A (sodium channel, nonvoltage-gated 1 alpha) 100ul $325 In Stock
LC422000 SCNN1A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 182 and 459 of SCNN1A (Uniprot ID#P37088)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Human) Concentration1mg/ml
Guaranteed Application * Suggested Dilutions
Predicted MW Explanation 76kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Human (100%)

Reference Data

Target NameHomo sapiens sodium channel, non voltage gated 1 alpha subunit (SCNN1A), transcript variant 1
Alternative NameBESC2; ENaCa; ENaCalpha; SCNEA; SCNN1
Database LinkNP_001029
Entrez Gene 6337 Human
FunctionNonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
Related PathwayIon Channels: OtherTransmembraneDruggable Genome Taste transduction

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