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Home Antibody All anti-PRKAA2 antibodies

Anti-PRKAA2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308756
  • Rabbit Polyclonal antibody to AMPK alpha 2 (protein kinase, AMP-activated, alpha 2 catalytic subunit)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC416772) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for PRKAA2 (NM_006252)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 29 and 480 of AMPK alpha 2
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.55mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens protein kinase, AMP-activated, alpha 2 catalytic subunit (PRKAA2)
Alternative NameAMPK; AMPK2; AMPKa2; PRKAA
Database LinkNP_006243
FunctionThe protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq]
Related Pathway

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WB Image
Sample (30 ug of whole cell lysate) A:NIH-3T3 ( anti-PRKAA2 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using AMPK alpha 2(anti-PRKAA2 antibody) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using AMPK alpha 2(anti-PRKAA2 antibody) antibody at 1:200 dilution.

 

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